Program

Day 1 - Gene expression analysis

  • Lecture 1: General processing of NGS data
  • Lab 1: Hands-on processing of RNA-seq data using FastQC, trim_galore, and alignment.
  • Lecture 2: Quantification of gene expression
  • Lab 2: Quantification and differential gene expression by RNA-seq

Day 2 - Chromatin accessibility

  • Lecture 3: Introduction to general epigenomics concepts
  • Lab 3: Processing MNase-seq data
  • Lecture 4: Peak calling and accessibility visualization
  • Lab 4: ATAC-seq peak calling and analysis

Day 3 - Chromatin composition

  • Lecture 5: Introduction to ChIP-seq
  • Lab 5: Integrating ChIP-seq peaks and genomic annotations
  • Lecture 6: DNA motif methodologies and resources
  • Lab 6: Meme and TFBSTools for motif enrichment analysis in R

Day 4 - Chromatin interactions

  • Lecture 7: Profiling chromatin contacts and visualize Hi-C data
  • Lab 7: Alignments and quality assessment using hicstuff
  • Lecture 8: Identifying structural features from Hi-C data
  • Lab 8: Levering chromosight to study chromatin contacts

Day 5 - Data integration and multi-omics

  • Lecture 9: Integrating multi-omics data through GO analysis
  • Lab 9: Combining RNA-seq, ATAC-seq, ChIP-seq and Hi-C data with Bioconductor
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