I am an Assistant Research Professor at the CNRS, based at the Institut Pasteur (Dept. of Genetics and Genomics) in Paris. Between 2020 and 2025, I worked as a postdoctoral researcher at the Institut Pasteur in Romain Koszul’s Spatial Regulation of Genomes laboratory.
I am working on developing biology-oriented methodologies to model dynamics of multi-modal chromatin organization and its impact on gene regulation across biological systems. I have contributed to developing data structures and tools for genome-wide omics data, including momics for deep-learning applications, the tidyomics ecosystem and the HiCExperiment suite of R packages. I come from an experimental biology background, transitioned toward combined “wet/dry” research during my Ph.D., and eventually focused entirely on computational data analysis during my postdoctoral work.
Prior to joining the Institut Pasteur, I earned my Ph.D. in Genetics from the University of Cambridge, studying under Julie Ahringer. While there, I conducted research on tissue-specific and developmentally-regulated gene expression in Caenorhabditis elegans. Before pursuing my Ph.D., I earned my Master’s degree in Genetics from the École Normale Supérieure de Cachan in 2016, and was a visiting researcher in the Plath laboratory at UCLA in 2015, where I focused on the molecular mechanisms underpinning chromosome-wide gene silencing by Xist long non-coding RNA.
My main research interests have covered a wide range of topics, including:
- Facilitating use of multi-omics data for deep-learning applications;
- Deciphering principles of 3D genome organization in microeukaryotes;
- Modeling cell cycle-like transcriptional dynamics during mouse cell differentiation;
- Profiling tissue-specific regulatory landscape in C. elegans.
For a full record of my publications, see Pubmed.
In addition to biology research, I develop computational frameworks for analyzing multi-omics and high-dimensional biological data. I maintain over a dozen python and R packages, published either on PyPI or Bioconductor. In 2024, I was elected as a member of the Bioconductor Technical Advisory Board for a three-year term, contributing to the strategic direction of the project.
If you are working in a company and would like help with some analysis or one of my packages, don’t hesitate to get in touch, as I am happy to consult on projects.